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Researchers suggest GR be considered a potentially protective biomarker against cognitive decline and Alzheimer's (Park 2023)

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Serum vitamin E concentrations are decreased in dogs with immune-mediate hemolytic anemia, 28 and hepatic glutathione concentrations are decreased in dogs and cats with various hepatic diseases

OS also reduces tetrahydrobiopterin (BH4), a critical cofactor for eNOS, causing it to produce more ROS instead of NO, thereby amplifying endothelial injury (Kavurma et al., 2022)

For example, research on oxidative stress and its impact on hair suggests that a balanced antioxidant status is vital for protecting hair follicles from damage (Treb, 2009)